Scientific Summary - Evidence-Based Gum Disease Treatment
Gum disease and peri-implantitis are common issues in dentistry that can lead to tooth and implant loss. Traditional treatments like scaling and root planing may not be enough to stop the inflammation and promote tissue regeneration. Horch (2018) introduced a unique non-antibiotic approach using active oxygen technology: OXYSAFE®, developed by Ardoz Healthcare International and marketed by Hager & Werken in Germany.
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Mechanism of Action of Active Oxygen
OXYSAFE® utilizes a patented active oxygen method that oxidizes protein structures in bacterial biofilms when in contact with the oral mucosa. This effectively deactivates anaerobic pathogens deep in gum and peri-implant pockets, unlike chlorhexidine and antibiotics.
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Clinical Effects and Scientific Backing
Studies show reduced pocket depth, inflammation, and improved gum health with OXYSAFE®. Research by Radboud University Nijmegen demonstrated a significant decrease in harmful bacteria and up to 56% reduction in pocket depth. Partial re-osseointegration was observed in 75% of peri-implantitis cases, including smokers, and over 80% wound healing in diabetic patients.
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Biocompatibility and Patient Safety
OXYSAFE® is biocompatible, non-cytotoxic, and does not harm blood cells, mucosal cells, or bone cells. Its safe application in initial and maintenance phases of gum and implant therapy sets it apart.
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Dual Treatment Concept
The treatment involves professional application of OXYSAFE® Perio Protection Gel by the dentist in affected pockets, followed by patient use of OXYSAFE® Liquid Mouthwash at home. This dual approach ensures lasting gum health and reduces infection recurrence.
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Significance for Modern Dentistry
OXYSAFE® aligns with the demand for minimally invasive, evidence-based, and antibiotic-sparing strategies in dentistry. It offers dental professionals a scientifically proven option for effective treatment and patient safety.
For more information on innovative dental solutions, visit Ardoz.com to explore knowledge, materials, and technology supporting premium oral care.